George Hopkins was born and raised in Cherry Hill, a neighborhood in south Baltimore. He graduated from Poly High School and then Morgan State University as a student-athlete where he got involved with the Fellowship of Christian Athletes (FCA). After earning his degree he worked full-time with FCA in Baltimore City and then he served as a pastor at Grace Fellowship Church in Timonium. In 2014 he partnered with twenty people to launch Sowebo Community Church—a multi-cultural church actively engaged with the community in Southwest Baltimore. For eight years George led a diverse church committed to serving the community and partnering with local leaders to strengthen the neighborhood. 

In 2018 he joined BUILD (Baltimoreans United In Leadership Development) and was elected as a Co-Chair in 2020 where he continues to serve with leaders throughout the city to empower Baltimoreans to build their own future in partnership with political, corporate, and philanthropic leaders.